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Mood Support

  • Serotonin Levels
  • Mood Balance
  • Sleep Support
  • Appetite Regulation
  • 100 mg Capsules
  • 90 Capsules per Bottle
  • 1 Capsule per Day

Promotes balanced and positive moods

Regular price $48.99

Unit price per 

A message from Dr. Nandi


Expertly Formulated

Experience greater calm, reduced pain, better sleep, and increased feelings of overall well-being.

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Why is Serotonin so Important?

Research shows that serotonin helps to regulate mood and behavior, so it has a positive effect on mood, relaxation, sleep, stress, appetite and even reduces pain.

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Highest Quality Ingredients

Mood Support is 100% pure and packs much more potency than competitors

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Recommended By Partha Nandi MD

“Anxiety and depression have become our “second pandemic.” I see it daily in my practice with so many patients suffering with no end in sight. I wanted to develop a safe and effective supplement to help my patients get through these downtimes. It’s tough for me to witness firsthand, how these symptoms affect them. 

I can see how emotions affect my patient’s physical health in the form of worsening symptoms of stomach pain, heartburn,, indigestion, constipation, or diarrhea, just to name a few.

The Partha Nandi, MD Mood Support supplement can help elevate your mood and behavior. I have seen it work in many patients, and I hope it works for you!”

-Partha Nandi M.D., F.A.C.P

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The Science Behind Mood Support

Stress Management*

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Stressful lifestyles and poor diets often cause a depletion of serotonin levels. Mood Support has been used for many years to replenish serotonin levels and support a healthy mood and sleep cycle regulation. Supplementation with Mood Support has been shown to increase serotonin levels in the central nervous system. The essential amino acid, tryptophan is converted into Mood Support by the enzyme tryptophan hydroxylase.

Tryptophan hydroxylase can be inhibited by a number of factors including stress, insulin resistance, pyridoxine (vitamin B6) deficiency and insufficient magnesium levels. Supplementation with Mood Support bypasses the conversion of tryptophan to Mood Support and thus supports optimal levels of serotonin.[1,2] 

Mood Support also readily crosses the blood-brain barrier (BBB)  and bypasses competition with other amino acids, making it a more efficient precursor for serotonin production.[1-3]

Mood and Comfort*

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Adequate levels of serotonin are associated with a sense of calmness and relaxation.[1-4] Several studies have demonstrated that Mood Support supports a healthy frame of mind, good energy levels, comfortable movement and restful sleep.[1,5,6,7]

Published studies of doses between 100-600 mg/day have also shown Mood Support to support occasional headaches. [ 8-10]

Sleep Support*

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Clinical studies have shown Mood Support helps to maintain healthy sleep cycle regulation. Mood Support improves quality of sleep by extending the rapid eye movement (REM) phase as well as increasing the deep sleep stages of non-REM sleep without increasing total sleep time. In addition, Mood Support promotes the release of melatonin by the pineal gland inside the brain and increases the length of REM.[3,11] In children, supplementation with Mood Support may help support peaceful sleep[12] and decrease the incidence of night terrors.[13]

Mood Support has also been found to raise plasma cortisol levels, causing a transient increase in growth hormone (at 150 mg dose) and, in men only, to support healthy levels of thyroid stimulating hormone.[14,15]

Appetite Regulation*

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Mood Support has been found to assist with carbohydrate cravings. Mood Support is known to support normal hypothalamic regulation, which includes appetite homeostasis.[16] In one study, sublingual Mood Support administered 5 times per day for 8 weeks in adult overweight women significantly supported feelings of post-meal hunger satisfaction. [17]

An additional double-blind study using 900 mg daily of Mood Support was found to produce significant weight loss in obese women. Reduced carbohydrate intake and improved satiety was observed following Mood Support administration.[18]

FAQ: Mood Support

What does Mood Support do for you?

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Mood Support dietary supplements help raise serotonin levels in the brain. Since serotonin helps regulate mood and behavior, Mood Support may have a positive effect on sleep, mood, anxiety, appetite, and pain sensation.

Mood Support is not found in the foods we eat, although tryptophan is found in foods.

Is there a downside to taking Mood Support?

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The most common side effects include heartburn, stomach pain, nausea, vomiting, diarrhea, drowsiness, sexual problems, and muscle problems.

Are there side effects from taking Mood Support?

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Taking the recommended dose should be safe for most users. Large doses of 5-HTP such as 6-7 grams (or 6000-7000mg) per day have been shown to be unsafe. Mood Support recommends a safe 100mg daily dose.

Should I take Mood Support every day?

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There is no specific recommended daily allowance for Mood Support. Most people will take 50–100 mg per day. Make sure you read the label and talk to a doctor before taking any supplement.

Can I take Mood Support if I am pregnant or nursing?

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Do not consume this product if you are pregnant or nursing. Consult your physician for further information.

Does Mood Support make you sleepy?

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Mood Support helps to make serotonin. And, when serotonin is introduced to darkness or evening, it becomes melatonin. Melatonin is what helps you sleep. Becoming tired when taking Mood Support is normal because your body's biological clock is performing better.

Does Mood Support make you feel happy?

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Mood Support is an important supplement that can help boost mood, regulate appetite, and manage pain.

Does Mood Support cause weight gain?

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Known for its ability to promote weight loss, Mood Support has been shown to reduce appetite. It appears to do this by stimulating serotonin production in the brain.

What is 5-Hydroxytryptophan?

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5-hydroxytryptophan (5-HTP) is a chemical that the body makes from tryptophan (an essential amino acid that you get from food). After tryptophan is converted into 5-HTP, the chemical is changed into another chemical called serotonin (a neurotransmitter that relays signals between brain cells). Mood Support dietary supplements contain 100mg of 5-HTP and may help raise serotonin levels in the brain.

Since serotonin helps regulate mood and behavior, Mood Support may have a positive effect on sleep, mood, anxiety, appetite, and pain sensation.

Does Mood Support work immediately?

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Every person is a bit different in how they respond to Mood Support but most people notice an effect in their quality of sleep by the six to twelve-week mark.

Symptoms of Low Serotonin

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Poor Sleep Quality

Chronic Pain

Memory Issues

Learning Struggles


Appetite issues

Mood issues

What Causes Issues with Serotonin?

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Hormonal Shifts


Lack of sunlight

Poor nutrition


Some Medications


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1. Juhl JH. Fibromyalgia and the serotonin pathway. Altern Med Rev 1998 Oct;3(5):367-75. 

2. Gutknecht L, Jacob C, Strobel A, et al. Tryptophan hydroxylase-2 gene variation infuences personality traits and disorders related to emotional dysregulation. Int J Neuropsychopharmacol 2007 Jun;10(3):309-20.

3. Birdsall TC. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev 1998;3(4):271-80.

4. Agren H, Reibring L, Hartvig P, et al. Low brain uptake of L-[11C]5-hydroxytryptophan in major depression: a positron emission tomography study on patients and healthy volunteers. Acta Psychiatr Scand1991;83(6):449-55.

5. Zmilacher K, Battegay R, Gastpar M. L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression. Neuropsychobiology 1988;20(1):28-35.

6. Caruso I, Sarzi Puttini P, Cazzola M, et al. Doubleblind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. 1990 May-Jun;18(3):201-09.

 7. Puttini S, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study J Int Med Res. 1992 Apr;20(2):182-89.

8. Ribeiro CA. L-5-hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo controlled study. Headache 2000 Jun;40(6):451-56.

9. Nagata E, Shibata M, Hamada J, et al. Plasma 5-hydroxytryptamine (5-HT) in migraine during an attack-free period. Headache 2006;46(4):592-96.

10. Nicolodi M, Sicuteri F. L-5-hydroxytryptophan can prevent nociceptive disorders in man. Adv Exp Med Biol. 1999;467:177-82.

11. Wyatt RJ, Zarcone V, Engelman K, et al. Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalogr Clin Neurophysiol. 1971 Jun;30(6):505-09.

12. Bruni O, Ferri R, Miano S, et al. L -5-hydroxytryptophan treatment of sleep terrors in children. Eur J Pediatr 2004;163(7):402-07.

13. Bruni O, Ferri R, Miano S, Verrillo E. L -5-Hydroxytryptophan treatment of sleep terrors in children. Eur J Pediatr. 2004 Jul;163(7):402-7. Epub 2004 May 14.

14. Lee MA, Nash JF, Barnes M, et al. Inhibitory effect of ritanserin on the 5-hydroxytryptophan-mediated cortisol, ACTH and prolactin secretion in humans. Psychopharmacology (Berl) 1991;103(2):258-64.

15. Mashchak CA, Kletzky OA, Spencer C, et al. Transient effect of L-5-hydroxytryptophan on pituitary function in men and women. J Clin Endocrinol Metab1983; 56(1):170-76.

16. Schott DA, Nicolai J, de Vries JE, et al. Disorder in the serotonergic system due to tryptophan hydroxylation impairment: a cause of hypothalamic syndrome? Horm Res Paediatr 2010;73(1):68-73.

17. Rondanelli M, Klersy C, Iadarola P, et al. Satiety and aminoacid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation. Int J Obes (Lond) 2009;33(10):1174-82.

18. Cangiano C, Ceci F, Cascino A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr 1992;56:863-867.

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