ReFresh is one of the most comprehensive formulas available on the market today

How does it work?

ReFresh is a unique probiotic formula designed to maintain a healthy vaginal microflora and support urogenital health. A healthy vaginal environment is mildly acidic, and therefore Lactobacillus species dominate this ecosystem. ReFresh provides two specific species of Lactobacilli: L. reuteri and L. rhamnosus. These two species are backed by human clinical studies to establish a healthy, stable vaginal ecosystem.

Vaginal and urogenital health issues are prevalent among women, with millions of people facing problems such as bacterial vaginosis, yeast infections, and urinary tract infections (UTIs) every year. According to the Centers for Disease Control and Prevention (CDC), bacterial vaginosis affects around 21.2 million women between the ages of 15 and 49 in the United States, while approximately 75% of women will experience at least one yeast infection in their lifetime. Furthermore, UTIs are the most common bacterial infections, with over half of all women experiencing at least one UTI during their lives. These issues can cause discomfort, pain, and distress, negatively impacting daily life and overall well-being.

RepFresh, with its blend of Lactobacillus species and Lactobacillus rhamnosus, offers a natural and effective solution to these widespread health concerns. By helping to maintain a healthy vaginal microflora, supporting urogenital tract health, establishing a healthy vaginal pH, and removing unwanted vaginal organisms, this product can prevent and alleviate symptoms associated with these common health issues. Taking RepFresh can lead to improved vaginal and urogenital health, reducing the risk of infections and promoting overall well-being. As part of a proactive approach to self-care, women can incorporate RepFresh into their daily routine to protect themselves from the discomfort and distress caused by these prevalent health problems.

Overview

Every area of the human body has a unique ecology and therefore a unique microbiome. The gut microbiome is spoken about frequently, but less commonly discussed are the specific microbiomes contained in other areas such as the skin, the lungs, the mouth, and even the vagina. The vaginal microbiome is abundant in Lactobacillus species, as they contribute heavily to the production of lactic acid. The lactic acid maintains a pH of 4, which if elevated, is a risk for vaginal microbiome challenges. Urogenital concerns are experienced frequently by women, and the most common interventions do little to address the state of vaginal ecology, and therefore, repeated challenges are often experienced. Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 have been studied and proven to support healthy vaginal ecology and promote microbial balance.

Probiotics in Vaginal Microbial Balance

Twelve to 50% of women worldwide experience vaginal microbiome challenges that significantly impact their quality of life.1,2,3 In several clinical studies, daily intake of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 were shown to promote the health of the vaginal microbiota. In another study, women with vaginal microbiome challenges were randomized to receive placebo or Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. After 6 weeks, significantly more women in the probiotic group maintained a balanced vaginal microbiota compared to women in the placebo group.4

A study of post-menopausal women with vaginal microbiome challenges were randomized to receive a placebo or Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. After four weeks, the women who received the probiotic blend maintained a healthy vaginal microbiota within the normal, beneficial range, whereas the balance of vaginal bacteria of the women in the placebo group was not significantly improved.1,5,6

Probiotics and Urogenital Health Urinary tract microbiome challenges are very common, impacting 150 million people each year. The specific blend of probiotics in ReFresh has been associated with supporting vaginal and urinary tract health. Specifically, studies suggest these probiotics promote vaginal and urinary tract health when used alone or in combination with common interventions. In other studies, participants consuming this specific probiotic blend maintained a healthy urinary tract microbiota with fewer incidence of urinary tract challenges.7,8,9

Directions 1 capsule per day or as recommended by your health care professional.

Does Not Contain Gluten, yeast, artificial colors or flavors.

Cautions If you are pregnant or nursing, consult your physician before taking this product.

References

1. Bradshaw CS, et al. Prevalent and Incident Bacterial Vaginosis Are Associated with Sexual and Contraceptive Behaviours in Young Australian Women. PLoS One. 2013;8(3):e57688.(PubMed) 2. Allsworth JE, Peipert JF. Prevalence of bacterial vaginosis: 2001-2004 National Health and Nutrition Examination Survey data. Obstet Gynecol. 2007;109(1):114-20. (PubMed) 3. Chico RM, et al. Prevalence of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review. JAMA. 2012;307(19):2079-86. (PubMed) 4. Vujic G, et al. Efficacy of orally applied probiotic capsules for bacterial vaginosis and other vaginal infections: a double-blind, randomized, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. 2013;168(1):75-9. (PubMed) 5. Foxman B, et al. Prevalence of recurrent vulvovaginal candidiasis in 5 European countries and the United States: results from an internet panel survey. J Low Genit Tract Dis. 2013;17(3):340-5. (PubMed) 6. Corsello S, et al. An epidemiological survey of vulvovaginal candidiasis in Italy. Eur J Obstet Gynecol Reprod Biol. 2003;110(1):66-72. (PubMed) 7. Flores-Mireles AL, et al. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015;13(5):269-84. 8. Ceccarani C, et al. Diversity of vaginal microbiome and metabolome during genital infections. Sci Rep. 2019;9(1):14095. (PubMed) 9. Brubaker L, Wolfe A. The urinary microbiota: a paradigm shift for bladder disorders? Curr Opin Obstet Gynecol. 2016;28(5):407-12. (PubMed)

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